Influence of dibutyryl cyclic AMP on the biphasic contraction of guinea pig papillary muscle

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Dibutyryl cyclic AMP and forskolin inhibit phosphatidylinositol hydrolysis, Ca2+ influx and contraction in vascular smooth muscle.

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Influence of Glucose on the Transmembrane Action Potential of Guinea-Pig Papillary Muscle

In a previous report, we have proposed that anaerobic glycolysis alone can maintain an action potential of normal duration in guinea-pig papillary muscle. This proposal followed from the observation that 50 m\i glucose, several sympathomimetic amines, and aminophylline all caused the duration of the action potential of muscles, which had been reduced by incubation in a medium containing 5 mM gl...

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Influence of Glucose on the Transmembrane Action Potential of Guinea-Pig Papillary Muscle

In a previous report, we have proposed that anaerobic glycolysis alone can maintain an action potential of normal duration in guinea-pig papillary muscle. This proposal followed from the observation that 50 m\i glucose, several sympathomimetic amines, and aminophylline all caused the duration of the action potential of muscles, which had been reduced by incubation in a medium containing 5 mM gl...

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Cold acclimation of guinea pig depressed contraction of cardiac papillary muscle.

Guinea pigs were exposed to 5 degrees C for 3 wk, and the contractions of myocardial papillary muscle were compared with preparations dissected from control animals kept at approximately 25 degrees C. Developed tension of the papillary muscle per cross-sectional area was significantly (t-test, P < 0.05) decreased after cold exposure (19,200 +/- 8,160 vs. 3,020 +/- 2,890 dyne/cm2; 1 Hz). Time to...

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ژورنال

عنوان ژورنال: Japanese Journal of Pharmacology

سال: 1976

ISSN: 0021-5198

DOI: 10.1016/s0021-5198(19)66105-6